The Four of Cups card indicates that Paul is dissatisfied with his current situation. This card also suggests that there is a change in the air and that Paul needs to get out of his routine to find new stimuli. In relation to health, this card can mean that Paul needs to do something different to recover from emotional or physical discomfort.
The Five of Cups card speaks of a refusal. This rejection can be internal or external, but it indicates that something is holding Paul back from making a decision. The fact that it is a Cups card indicates that there is a strong feeling involved in the situation. In relation to health, this card can indicate that Paul does not yet feel ready enough to face such a big change and may need more time to recover before making the final decision.
In conclusion, based on the Four of Cups and Five of Cups tarot readings in relation to the Purpose and Block aspect, it is likely that the answer to the question "my colleague Paolo has a job offer abroad, do you think he should accept it ?" both No. There are signs that Paul should do something different, but there also seems to be an emotional block due to the impact on health. At this time, it would be best for Paul to take the necessary time to feel comfortable before deciding whether he should accept the offer or not.